ترجمه آماده – ساختار سیالات جریان خون بطن چپ دینامیک تحت پشتیبانی

Congestive heart failure is a serious health condition characterized by the inability of the heart to supply adequateblood flow and therefore oxygen delivery to the body. Due to limited availability of donor organs and limitations in drug therapies, many left ventricular assist devices (LVADs) have been developed. In order to optimize LVAD use in unloading the ventricle, a detailed understanding of the impact of the device on the hemodynamic variables in the ventricles, such as flow dynamics and pressure, as well as cardiac wall motion, is crucial [1]. This can be achieved through in vivo animal experiments, clinical trials, in vitro experiments and numerical models. Among these methods, computational fluid dynamics (CFD), which provides detailed flow characteristics in the ventricle, such as velocity profiles, shear rate, recirculation and pressure, have been widely used in the development of VADs [2]. CFD has been extensively used in the analysis and design of such LVADs, for example to determine the pressure-flow characteristics and efficiencies of the pump [۳,۴]. It has also been used to evaluate the thrombosis potential in the LVAD cannula with various geometrical designs.